Since 2015, Dr. Frangoul has served as the Medical Director of Pediatric Hematology/Oncology for the Sarah Cannon Center for Blood Cancer at The Children's Hospital at TriStar Centennial. He also serves as an investigator for Sarah Cannon Research Institute, focusing on the research and treatment of blood disorders for pediatric and adult patients, with a specialization in blood and marrow transplantation.

Dr. Frangoul is internationally recognized for his research and expertise in stem cell transplantation, having published more than 120 peer reviewed manuscripts and presented on more than 35 abstracts. Prior to joining Sarah Cannon and TriStar Health, Dr. Frangoul was the Director of the Pediatric Stem Cell Transplant program at Vanderbilt University from 1999-2014.